11 April

Opening Session

Grigori Enikolopov
Keynote speaker
  Center for Developmental Genetics of Stony Brook University   Maintenance and division of neural stem cells
Mark W. Lowdell
Keynote speaker
  University College London   Сell theraphy and clinical trials in tissue engineering
Hans R. Schöler
Keynote speaker
  Max Planck Institute for Molecular Biomedicine   Induction of Multi- and Pluripotent Stem Cells: Basic Science and Regenerative Potential



12 April

Basic Problems of Cell Research

Oleg Serov   Institute of Cytology and Genetics RAS   Topic under discussion
Andrey Vasiliev    Koltzov Institute of Developmental Biology of Russian Academy of Sciences   Insulin producing cells from non-prancreatic source
Egor Vasetsky   Institut Gustave Roussy   Cell therapy approaches for Facioscapulohumeral dystrophy
Alexey Tomilin   Institute of Cytology RAS   New players in the field of pluripotency.


Cellular Disease Modeling

Sergey Nedospasov   Institute of molecular biology, Moscow State University   Topic under discussion
Maria Lagarkova   Vavilov Institute of General Genetics RAS   Study of molecular mechanisms of socially significant human diseases using cellular models  based on induced pluripotent human cells
Anna Malashicheva   Federal Almazov Medical Research Centre   iPSCs for cardio-vascular disease modelling
Konstantin Yarygin   Institute of Biomedical Chemistry   Mechanisms of the effects of cell therapy in the middle cerebral artery occlusion model of ischemic stroke
Natalia Kalinina   Faculty of Fundamental Medicine, Moscow State University   Extracellular vesicles, mesenchymal stromal cells: involvement in tissue regeneration


 Organoids and Tissues Engineering Session

Jens Schwamborne   Université du Luxembourg   Advanced modelling of neurodegeneration with three-dimensional human midbrain organoids
Dmitry Papatsenko   Skolkovo   “Gene expression in single cells: how much new we can learn from the data”
Ekaterina Vorotelyak    Koltzov Institute of Developmental Biology of Russian Academy of Sciences   Skin tissue and organ regeneration
Andrey Panteleev   Natioonal Research Center “Kurchatov Institute”   Bioengineering a functional tracheal epithelium: matrices and cells
Fedulov A. V.   Moscow Regional Research and Clinical Institute (“MONIKI”)   Photocurable biodegradable implants based on methacrylated silk fibroin for the prevention and treatment of insolvency of the  gastrointestinal tract anastomosis



13 April

Genome Editing Session

Dominik Paquet   Ludwig-Maximilians University   A CRISPR-based gene editing framework allows modelling early-onset Alzheimer’s disease in genetically defined human iPSC lines
Erdem Dashinimaev   Koltsov Institute of Developmental Biology RAS   Genes knockout in induced pluripotent cells with CRISPR/Cas9 and clones selection  using droplet digital PCR


Best Practice in Cell Therapy and Cell Products Development

Stephen Sullivan   Global Alliance for iPSC Therapies   Facilitating the therapeutic use of HLA homozygous clinical-grade induced pluripotent stem cell lines’
Vladimir Baklaushev   Federal Scientific and Clinical Center of Special Means of Medical Assistance and Medical Technologies FMBA Russia   Regenerative treatment of spinal cord injury.


Round Table: Best Practice and Challenges in Cell Technologies Commercialization

At the end of the day the main goal of all cell technology research activities is to translate the results of basic science into therapeutics that helps patients. This round table allows the conference participants to get more deep understanding of the existing  standards and regulations in Russia and European Union related to cell therapy translation into practice. Representatives from the Russian Ministry of health, from the leading cell technology centers from Russia and EU will share their experience and discuss actual challenges in biomediclal cell products practical application, registration, foundng cell banks, etc.