april 11-13, 2018 | Moscow
CTERP INTERNATIONAL CONFERENCE
Translational Research in Cell Therapy
Welcome to the II International CTERP Conference. It meets the most acute demands of the burgeoning research activities both in novel cell therapy methods and disease mechanism understanding — iPSC, neurobiology, disease modelling, genome editing.

Recently passed law on cell technologies in Russia opens new perspectives for cell technology practical application but also calls for careful understanding of regulation requirements. Regulatory aspects in Russia and abroad will be discussed on the round table.

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Adress
2 Presnenskaya Naberezhnaya
Novotel Moscow City, Moscow

Participation cost
from 2500 RUR
New York, USA
Grigori Enikolopov
Professor at the Center for Developmental Genetics of Stony Brook University
Adjunct Professor at Cold Spring Harbor Laboratory
Adjunct Professor at Moscow Institute of Physics and Technology


Graduated in neurobiology and molecular biology from Moscow State University. Received his Ph.D. at the Institute of Molecular Biology in Moscow. Worked at the Institute of Molecular Biology, with training at the University of Zurich. Since 1989 worked at Cold Spring Harbor Laboratory, before recently joining Stony Brook University.

Research interests
  • stem cells of the adult brain
  • signals controlling division, differentiation, and maintenance of stem cells
Novosibirsk, Russia
Dmitry Zharkov
Doctor of Science in Biology
SB RAS Institute of Chemical Biology and Fundamental Medicine
Head of the Laboratory of Genome and Protein Engineering at SB RAS Institute of Chemical Biology and Fundamental Medicine
Director of the Interdisciplinary Center for Advanced Biomedical Research at Novosibirsk State University


  • 2015 Russian Academy of Sciences Professorship.
  • 2015 Russian Foundation for Basic Research Certificate of Honor for contribution to the development of science.
  • 2014 Novosibirsk State University Certificate of Honor for lifetime contribution for the benefit of the University.
  • 2009 Prize of the Government of Novosibirsk Region for achievements in science and technology.
  • 2007 Russian Academy of Sciences Honorary Award for achievements in basic sciences and industry in Siberia.

Obtained a PhD in 1998 from the Stony Brook University, USA. From 1998 to 2001, he was a postdoc at the Department of Pharmacological Sciences, Stony Brook University and worked as a visiting scientist at the Weizmann Institute of Science, Israel. During his career, Dr. Zharkov contributed to the discovery of several DNA repair enzymes and understanding their mechanism of action through biochemical, structural, and computational studies.

Presently, he heads the Laboratory of Genome and Protein Engineering at SB RAS Institute of Chemical Biology and Fundamental Medicine, and is the director of the Interdisciplinary Center for Advanced Biomedical Research at Novosibirsk State University (NSU). He teaches Molecular Biology and Molecular Pharmacology at NSU.

Research interests:
  • Fundamental mechanisms of DNA damage, DNA repair and cell response to genotoxic stress.
  • Human diseases linked to genotoxic stress and DNA repair defects.
  • Development of molecular biology tools employing DNA repair enzymes.
  • Design of enzymes and protein/nucleic acid systems with predicted functions and properties.
  • Development of new tools for genome editing.
Professional membership:
  • European Environmental Mutagen Society
  • Russian Biochemical Society
  • Yu. A. Ovchinnikov's Russian Society of Biotechnologists.
    Moscow, Russia
    Sergei Nedospasov
    Professor
    Doctor of Biological Sciences
    Corresponding Member of the Russian Academy of Sciences
    Academician of the Russian Academy of Sciences
    Head of the Laboratory of Molecular Mechanisms of Immunity, Engelhardt Institute of Molecular Biology RAS
    Head of the Department of Molecular Immunology, Institute of Physico-Chemical Biology RAS
    Head of the Department of Immunology, Biological Faculty, Moscow State University
    Scientific Supervisor of the Laboratory of Experimental Immunology of the Center for Molecular Biology and Biomedicine, Institute of Biology and Biomedicine, Nizhny Novgorod State University


    • Graduated from Faculty of Molecular and Chemical Physics, Department of Molecular Biophysics
    • From 1976 he worked in the laboratory of Acad. G.P. Georgieva in the Institute of Molecular Biology. Engelhardt of the Russian Academy of Sciences, then headed a scientific group and a laboratory at the same Institute
    • In MSU - since 1996 (Institute of Physico-Chemical Biology named after AN Belozersky)
    • From 1995 to 2010 - International Research Scholar Medical Institute. Howard Hughes
    • In 1980 he defended his Ph.D. thesis, in 1990 he obtained his doctoral thesis
    • Since 1998, Professor. He is in charge of the Laboratory of Molecular Mechanisms of Immunity of the Institute of Molecular Biology, Russian Academy of Sciences. V. A. Engelhardt.

    Russian biologist, an expert in molecular biology and genetics, immunology and biotechnology. One of the top 100 most cited Russian scientists.

    He organized educational programs in Moscow on oncoimmunology and molecular immunology.
    Made a major contribution to the development of domestic molecular biology, immunology and biomedicine. He and his school carried out pioneering work on the biology of cytokines, created unique animal models of human diseases, investigated the mechanisms of pathogenesis of a number of diseases at the molecular level, developed new approaches to biotherapy, including the creation of prototypes for new drugs.

    In the 80 years, SA Nedospasov and colleagues were the first to molecularly clone the genes of the tumor necrosis factor family of cytokines, which are the mediators of immune processes. Based on these molecular clones, cytokine production strains have been created in our country, including TNF and human lymphotoxin, and then a panel of monoclonal antibodies that neutralize their activity. SA Nedospasov and colleagues created a unique panel of mouse lines with controlled deactivation of TNF, lymphotoxin and other mediators important for the development of the immune system. In these animals it became possible to model various human diseases - from autoimmune and infectious to oncological, to study the association of microbiota with inflammation, and also to practice biotherapy.

    Published more than 200 articles, including in the leading international journals: Science, Nature, Immunity, Blood.

    Member of the editorial boards of international and domestic journals: European Journal of Immunology, Journal of Inflammation, Immunology Letters, Molecular Biology, Russian Immunological Journal, Medical Immunology, Cytology.

    Scientific interests:
    • mechanisms of innate immunity
    • physiology of cytokines
    • genetic knockout in mice and mouse models of human diseases
    • cancer antigens.

    Awards
    • Investigator Award of the Institute of Cancer Research (USA, 1991)
    • Prize of the Berlin-Brandenburg Academy of Sciences (Germany, 2000)
    • The Helmholtz-Humboldt Prize (2005)
    • Elected a member of the European Academy (2010), the European Academy of Oncoimmunology (2012)
    • II Mechnikov Prize (2011) - For the cycle of scientific works "Molecular-cellular mechanisms of organization of human and mouse lymphoid organs" (jointly with AA Yarilin).
    • The State Prize of the Russian Federation (2015) - for a series of fundamental and applied works on the study of molecular mediators of immunity, including works on the creation of unique biomedical models.
    • Honorary Doctor of UNN. NN Lobachevsky (2016).
    Moscow, Russia
    Vladimir Baklaushev
    MD, PhD, DSc (med)
    Chief Scientific Officer Federal Research and Clinical Center, FMBA of Russia
    Professor of the Department of Laboratory Diagnostics, Institute of Medical Advanced Training FMBA of Russia


    • 2002 – 2014 Senior Research Fellow, Department of Fundamental and Applied Neurobiology, Serbsky National Research Centre for Social and Forensic Psychiatry
    • 2008 – 2009 Assistant Professor, Chair of Medical Nanobiotechnology, N.I. Pirogov Russian State Medical University
    • 2009 – 2016 Associate Professor, Chair of Medical Nanobiotechnology, N.I. Pirogov Russian State Medical University
    • 2014 – present time. Chief Scientific Officer Federal Research and Clinical Center, FMBA of Russia
    • 2016 - present time. Professor of the Department of Laboratory Diagnostics, Institute of Medical Advanced Training FMBA of Russia.

    Scientific interests:
    • Neuroscience, Blood-Brain Barrier, Targeted Delivery into the Brain, Cell therapy of spinal cord injury, Cell therapy of Stroke
    • Tissue engineering of nervous system. Immunotherapy of solid tumors
    • Therapy of autoimmune diseases with T-regs.
      London, UK
      Mark Lowdell
      PhD FRCPath FRSB
      Professor of Cell & Tissue Therapy at University College London
      Director of the Centre for Cell, Gene & Tissue Therapeutics
      Honorary Consultant Immunologist at Royal Free Hospital London
      Qualified diagnostic immunopathologist as well as holding MHRA Qualified Person status for the release of ATMPs for clinical trials
      Сurrent Vice President (Europe & Middle East) of the
      International Society for Cell Therapy



      Has over 20 years' experience in adoptive immunotherapy of cancer and has focussed on the role of the innate immune responses; especially the role of natural killer (NK) cells. Particularly interested in translational research and established the first academic GMP facility in the UK for the production of human cells as medicines in 2001. This GMP facility now produces somatic cell medicines, gene therapies and tissue engineered products. Professor Lowdell led the technology transfer of his own adoptive NK cell therapy product into three commercial CMOs in the US and was the chief scientific officer for the US clinical trial.

      His interest in clinical translation of cell and tissue therapies led to him being responsible for the first GMP-compliant stem cell-derived airway transplant produced as an ATMP in the EU and he now holds >£12m funding to perform formal clinical trials of stem cell derived trachea and larynx as well as the first UK clinical trial of an iPS cell-derived product. His newly refurbished ATMP GMP suite at RFH consists of 10 state-of-the-art manufacturing labs and over 20 staff supporting multiple academic and commercial trials.

      Scientific awards and memberships
      Professor Lowdell has held and holds numerous appointments to academic and government advisory boards in the UK and overseas. Recently he was a member of the UK Government Regenerative Medicine Expert Review Group and is a member of the scientific advisory boards, consultant to or founder of many of the key companies involved in ATMP development in the EU and USA including Autolus Ltd, Achilles Therapeutics Ltd, Cell Medica Ltd, InmuneBio Inc, NWBio Therapeutics.
      Münster, Germany
      Hans Schöler
      Director and Scientific Member at the Max Planck Institute for Molecular Biomedicine


      • 1985 Studies in biology in Heidelberg, doctorate
      • 1994 German Habilitation in molecular biology Ruprecht Karl University Heidelberg
      • 1991-1999 Head of a research group at EMBL Heidelberg
      • 1999-2004 Full Professor of Reproduction Physiology at the School of Veterinary Medicine and Director of the Center of Animal Transgenesis and Germ Cell Research at the University of Pennsylvania/USA
      • Since 2004 Adjunct Professor of Biochemistry, University of Pennsylvania, School of Veterinary Medicine, Department of Animal Biology, Philadelphia/USA
      • Since 2003 Director and Scientific Member at the Max Planck Institute for Molecular Biomedicine.

      Scientific awards and memberships
      • 2004 Member of "Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften"
      • 2005-2013 Head of the Managing Board of the Stem Cell Network North Rhine Westphalia
      • 2005 Member of the "Nordrhein-Westfälische Akademie der Wissenschaften" (North Rhine-Westphalian Academy of Sciences)
      • Since July 2005 Member in the "Zentrale Ethik-Kommission für Stammzellenforschung"
      • 2008 Robert Koch Prize
      • 2010 Extraordinary Member of the Berlin-Brandenburg Academy of Sciences and Humanities
      • 2010 Corresponding Member of the Academy of Sciences and Literature Mainz.
      Munich, Germany
      Dominik Paquet
      Dr. rer. nat.
      Professor of Neurobiology, Ludwig-Maximilians University, Munich
      Head of research group in the Institute for Stroke and Dementia Research


      • 2011-2016 Postdoctoral Fellow, Laboratory for Brain Development and Repair, The Rockefeller University, New York
      • 2009-2011 Postdoctoral Fellow, German Center for Neurodegenerative Diseases, Munich
      • 2005-2009 PhD Thesis (summa cum laude), Department of Biochemistry, Adolf-Butenandt-Institute, Ludwig-Maximilians University, Munich
      • 2004-2005 Diploma Thesis, MRC Centre for Developmental Genetics, University of Sheffield
      • 1999-2004 Studies of Biology (summa cum laude), University of Tuebingen.

      Prof. Dr. rer. nat. Dominik Paquet headed a research group in the Institute for Stroke and Dementia Research in the end on 2016. He was appointed Professor for Neurobiology and is a member of the Munich Cluster for Systems Neurology. Following his PhD at the LMU Munich, Prof. Paquet worked as a New York Stem Cell Foundation Druckenmiller Fellow in the laboratory of Marc Tessier-Lavigne, where he pioneered the use of CRISPR/Cas9 gene editing in induced pluripotent stem cells to study diseases of the human brain.

      His research at the ISD is focused on the molecular and cellular mechanisms leading to neuronal death and cognitive decline in patients with neuropsychiatric disorders (e.g. Alzheimer's disease and Frontotemporal dementia) and neurovascular impairments (stroke and vascular cognitive impairment). He plans to build advanced human in vitro model systems based on patient-derived cells that recapitulate major disease hallmarks, and thus facilitate molecular studies and accelerate the identification of novel therapeutic approaches.

      Research interests
      • molecular and cellular mechanisms leading to neuronal death and cognitive decline in patients with neuropsychiatric disorders
      • neurovascular impairments.
        Luxembourg, Belgium
        Jens Christian Schwamborn
        Université du Luxembourg, Faculté des Sciences, de la Technologie et de la Communication
        Principal Investigator in the Developmental & Cellular Biology group

        Since 2013 Jens C. Schwamborn, PhD, is head of the Developmental and Cellular Biology group at the Luxembourg Centre for Systems Biomedicine as well as Professor at the University of Luxembourg. Additionally, since 2016 Jens is Chief Scientific Officer of the biotech company Braingineering Technologies SARL.
        In 2002 Jens obtained a diploma in Biochemistry from the University Witten/Herdecke in Germany and in 2005 a PhD in Biology from the University Muenster in Germany. He worked as a postdoctoral researcher at the Institute for Molecular Biotechnology in Vienna / Austria.

        The focus of his work over the last years was on Neurobiology, Stem Cell research and Parkinson's disease. In particular he is interested in using human induced pluripotent stem cells for the development of advanced approaches for in vitro disease modeling. Jens published more than 50 papers in peer reviewed journals, holds several patents and severs as reviewer for numerous journals and funding agencies.

        Research Interests
        • Parkinson's disease
        • Systems Biomedicine
        • Stem Cells
        • Neurogenesis
        • Regeneration.
        London, UK
        Stephen Sullivan
        PhD MBA FRSM

        Dr Sullivan earned his PhD at the Roslin Institute (Edinburgh) under Professor Ian Wilmut and Dr Jim McWhir, becoming one of the first researchers in Europe to culture human embryonic stem cells. His work focused on pluripotency induction in human somatic cells. Thereafter, Dr Sullivan worked as a Research Fellow at the University of Cambridge, Harvard University, and UCSD deepening his expertise of other human stem cell types (including induced pluripotent stem cells) and their applications for human medicine. While at Harvard, he read 'How Economics Shapes Science' by Paula Stefan, which stimulated his interest in the financial, as well as the scientific and medical, hurdles that must be surmounted to bring stem cell therapies to the clinic.

        He also worked for Novartis, dealing with clinical trial management and compliance, to better understand the Industrial perspective on bringing novel therapies to market. Thereafter, he earned an MBA at Trinity College Dublin focusing on risk mitigation within the nascent pluripotent stem cell market. From 2008-2017, Dr Sullivan was the Chief Scientific Officer of the Irish Stem Cell Foundation, where working with others, he facilitated the introduction of stem cell legislation into the Irish Program for Government. He is an honorary associate of the Scottish National Blood Transfusion Service, a member of Human Pluripotent Stem Cell Advisory Committee at University College Cork, and Chief Editor of 'Human Embryonic Stem Cells – The Practical Handbook' published by Wiley & Sons.

        In June 2017, Dr Sullivan joined GAiT, a new initiative supporting implementation and clinical application of therapies derived from pluripotent stem cells for the benefit of patients globally. GAiT is supported by an international consortium of organisations including the Cell and Gene Therapy Catapult (London, UK), the Centre for Commercialisation of Regenerative Medicine (Toronto, Canada), the Korea HLA-Typed iPSC Banking Initiative (Seoul, Korea) and the New York Stem Cell Foundation (New York, USA).

        Scientific awards and memberships
        • Honorary associate of the Scottish National Blood Transfusion Service
        • Member of Human Pluripotent Stem Cell Advisory Committee at University College Cork
        • Chief Editor of "Human Embryonic Stem Cells – The Practical Handbook"
        • Global Alliance for iPSC Therapies member.
        St. Petersburg, Russia
        Alexey Tomilin
        Ph.D. Sci.D. Corresponding Member of the Russian Academy of Sciences
        Head of Laboratory of the Molecular Biology of Stem Cells, Institute of Cytology RAS


        Dr. Alexey Tomilin has broad interests in cell and molecular biology with a primary focus on pluripotent stem cells, such as embryonic stem (ES) and induced pluripotent stem (iPS) cells. Studying molecular mechanisms of stem cell maintenance and development is his primary focus, however, he also develops applications of pluripotent stem cells in clinics.

        • 1987-1992 Master Degree, Physics School, Polytechnical University, St-Petersburg
        • 1992-1997 Post-graduate training, Institute of Cytology, RAS, St-Petersburg and University of Caen, France; Ph.Ds. (Russian and French)
        • 1998: EMBO post-doctoral fellowship
        • 1998-1999 post-doctoral training, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany
        • 1999-2002 post-doctoral training, School of Veterinary Medicine, University of Pennsylvania, USA
        • 2002-2006 Junior group leader, Dept. Developmental Biology, Max-Planck Institute for Immunobiology, Freiburg, Germany
        • 2007-now Lab leader, Institute of Cytology RAS, St-Petersburg
        • 2009 D.Sc. degree
        • 2011 Elected Corresponding Member of the Russian Academy of Science
        • 2009-now Member of scientific and thesis defence board of the Institute of Cytology RAS
        • 2009-2016 Advisory Board member of the Int. Rev. Cell Mol. Biol.
        • 2011 Elected corresponding member of the RAS
        • 2013 Member of the progmam committee of the FEBS-2013
        • 2013-now Member of the Expert Board of the Russian Foundation of Basic Research;
        • 2014-now Member of Expert Board of the Russian Science Foundation;
        • 2014 Expert of the Presidium of the RAS programme "Fundamental research for the development of biomedical technologies"
        • 2014-now Member of Scientific Council of the Ministry of Health;
        • 2016 Сhair of the conference "Recent Achievements in Stem Cells Research", April 6-8, 2016, St. Petersburg, Russia
        • 2016 Member of selection committee of the 12-th International Congress of Cell Biology (ICCB 2016), Praha
        • 2016 Honorary medal "Silver Sigma" (Siberian Branch of the Russian Acad. Sci.)
        • 2017 Honorary Diploma of the Russian Academy of Sciences "For conscientious work, great contribution to the development of fundamental and applied science, in connection with the 60th anniversary of the foundation of the Institute of Cytology"
        • 2017 Member of program committee of the III National Congress of Regenerative Medicine, November 15-18, 2018, Moscow, Russia.
          Moscow, Russia
          Andrey Vasiliev
          Prof., Sci. Dr.
          Director of Koltzov Institute of Developmental Biology RAS


          Scientific interests
          • mechanisms of tissue repair
          • regenerative medicine.
          Moscow, Russia
          Maria Lagarkova
          Dr. Sci.(Biol.)
          Vavilov Institute of General Genetics, Laboratory of Stem Cell Biology
          Head of the Laboratory of Cell Biology at the Research Center of Physical-Chemical Medicine in Moscow.


          Graduated from the Lomonosov Moscow State University. She defended her PhD thesis "New approaches to study the loop organization of chromosomes" in 1995. For many years Maria Lagarkova works in the field of stem cell biology. She is a head of the Laboratory of Cell Biology at the Research Center of Physical-Chemical Medicine in Moscow. The basic directions of Maria Andreevna's scientific research are the study of the mechanisms of differentiation and epigenetics of pluripotent stem cells and the modeling of neurodegenerative diseases with induced pluripotent stem cells.

          Research interests
          • mechanisms of differentiation and epigenetics of pluripotent stem cells
          • neurodegenerative diseases with induced pluripotent stem cells.


          St. Petersburg, Russia
          Anna Malashicheva
          PhD
          Head of laboratory of Molecular Cardiology, Federal Almazov Medical Research Centre
          Associate Professor, Dept. of Embryology, Biological Faculty, St.-Petersburg State University


          Research interests
          • developmental biology
          • cellular and molecular biology of stem cells
          • translational medicine

          Ongoing projects in the laboratory
          • Lineage specific function of Notch signaling in the cardiovascular system, role of Notch signaling in aortic diseases and congenital heart diseases
          • Modeling of cardiomyopathies with patient-specific induced pluripotent stem cells
          • Notch in osteogenic differentiation.
          Moscow, Russia
          Erdem Dashinimaev
          PhD
          Koltzov Institute of Developmental Biology RAS

          Graduated from Moscow Institute of Physics and Technologics, Department of Molecular Biology and Physics. Defended thesis on the creation of immortalized cultures of human stem and progenitor cells by telomerase activation. At this moment works at the Koltsov Institute of Developmental Biology in the laboratory of cell biology.

          Research interests
          • stem cells
          • regenerative medicine
          • genome editing.
          Cardiff, UK
          Philip Stephens
          Professor of Cell Biology and Dean of International for the College of Biomedical and Life Sciences at Cardiff University
          HTA Designated Individual
          Cardiff University Biobank academic lead
          President of the European Tissue Repair Society

          Professor Philip Stephens is currently Professor of Cell Biology and Dean of International for the College of Biomedical and Life Sciences at Cardiff University. He moved to Cardiff University in 1994 as Post Doctoral Researcher having obtained a first class honours degree and a PhD from Leeds University. Subsequently he established the Wound Biology Group with a clinical colleague. He was previously Vice Dean (Research) at the School of Dentistry, Cardiff University and Chair of the Cardiff Institute of Tissue Engineering and Repair.

          His research interests are in the fields of oral progenitor cells, differential wound healing, ageing, tissue engineering, animal replacement model systems and cellular imaging. Within these areas he has managed research projects (Research Council, Charity and Industry) totalling over £4.5 Million, published widely, obtained patents and his group has won many National and International prizes.

          Externally he works closely with organisations such as the National Centre for the Replacement, Refinement and Reduction of Animals in Research and reviews grant applications and manuscripts for numerous national and international funders/journals. He is currently setting up an overarching tissue biobank at Cardiff University to support research in both academic and industrial settings.


          Research interests
          • oral progenitor cells
          • differential wound healing
          • ageing
          • tissue engineering
          • animal replacement model systems
          • cellular imaging.
          Moscow, Russia
          Alexander Fedulov
          Moscow Regional Research Clinical Institute

          In 2013 won of the "UMNIK" program with topic: "A new technique of treating infertility and restore of male testosterone generative function." Since 2015 - a scientific employee in the Department of Pediatric Surgery in the "Moscow Regional Research Clinical Institute". Member of the group of regenerative medicine in the "Moscow Regional Research Clinical Institute".

          At the moment, the scientific work is devoted to research of the effect of vitalized and non-vitalized biodegradable implants of various compositions on regeneration of the gastrointestinal tract, when it is damaged, in experiment.

          Research interests
          • regenerative medicine
          • cellular technologies
          • biodegradable implants
          • reconstructive operations on gastrointestinal tract.
          Moscow, Russia
          Konstantin Yarygin
          PhD, MD
          Head of the Cell Biology Lab at IBMC, Moscow, Russia
          Professor at the Department of Pathophysiology at the Russian Medical Academy of Postgraduate Education

          Academic Experience
          • 1974-1996 USSR Cardiology Research Center, Moscow, Russia
          • 1996-1998 Geraldine Brush Cancer Research Institute, California Pacific Medical Center, San Francisco, CA
          • 1998-present Orekhovich Institute of Biomedical Chemistry, Moscow, Russia
          • 2003-2007 Russian State Medical University, Moscow, Russia
          • 2013–present Russian Medical Academy of Postgraduate Education, Moscow, Russia

          Research Interests
          • regenerative medicine
          • cell biology
          • stem cells.
            Moscow, Russia
            Natalia Kalinina
            Leading research scientist in the Department of Biochemistry and Molecular Medicine, Faculty of Medicine, M.V. Lomonosov Moscow State University

            Graduated summa cum laude from Faculty of Biology, M.V. Lomonosov Moscow State University in 1997. In 2001, she got her PhD from Cardiology Research Center, Moscow, Russia. Currently she is a leading research scientist in the Department of Biochemistry and Molecular Medicine, Faculty of Medicine, M.V. Lomonosov Moscow State University.

            Studies of Dr. Kalinina are focused on cellular and molecular mechanisms of tissue regeneration; stem and progenitor cell physiology. In this field she has published over 50 articles, co-author of 19 RF patents.

            She was awarded by Rector stipend to young teachers and scientist achieved a significant success in teaching and research (2005 and 2007).

            Research interests
            • cellular and molecular mechanisms of tissue regeneration
            • stem and progenitor cell physiology.
            Moscow, Russia
            Ekaterina Vorotelyak
            PhD
            Corresponding member of Russian Academy of Sciences
            Head of the Cellular Biology laboratory at Koltzov Institute of Developmental Biology RAS
            Associate Professor at Moscow State University
            Head of the Department of Regenerative Medicine in Pirogov Russian National Research Medical University

            In 1993 Vorotelyak obtained a diploma in Cell Biology and Histology from Moscow State University and in 1998 a PhD in Biology. She worked as postdoctoral fellow in N.K. Koltzov Institute of Developmental Biology of Russian Academy of Sciences in Moscow. In 2016, she was elected as a Corresponding member of Russian Academy of Sciences.

            In recent years she focused on epidermal and hair follicle morphogenesis, mesenchymal and epidermal stem cells in the skin and development of new technologies for regenerative medicine. Vorotelyak published more than 60 papers in peer reviewed journals, holds several patents and severs as reviewer for numerous funding agencies.

            Research inrerests
            • epidermal and hair follicle morphogenesis
            • mesenchymal and epidermal stem cells in the skin
            • development of new technologies for regenerative medicine.
            Moscow, Russia
            Andrey Panteleyev
            PhD
            Head of the laboratory of Tissue engineering Kurchatov complex of NBICS technologies, Kurchatov institute

            • 1979 – 1985 Research Scientist, Scientific Department of Moscow Zoo
              social behavior of great apes and monkeys.
            • 1985 – 1994 Research Scientist, Severtsov Institute of Ecology and Evolution, RAS, Moscow
              Сomparative skin morphology in mammals, skin adaptation to environmental stress factors, skin toxicology.
            • 1989 – 1991 Intermittent studies (as a Senior Research Scientist) at Joint Russian-Vietnam Tropical Research Center, HoChiMinh City, Vietnam
              Skin effects of exposure to Agent Orange.
            • 1994 - 1995 Fellow (European Science Foundation Fellowship in Toxicology) and then the Research Associate, Department of Dermatology, Virchow Hospital and Institute of Toxicology and Embryopharmacology, Free University, Berlin, Germany
              Studies of dioxin skin toxicity using "hairless" mice.
            • 1996 – 1997 Research Scientist, Severtsov Institute of Ecology and Evolution, Russian Academy of Science, Moscow
              Skin toxicology, hairless "hr" gene functions in skin; the role of stem cells in hair follicle regeneration.
            • 1998 – 2000 Associate Research Scientist, Department of Dermatology, College of Physicians and Surgeons, Columbia University, New York, NY
              Molecular control of normal skin development and molecular genetics of heritable skin diseases, hair follicle stem cell kinetics and hair cycle, skin wound healing and regeneration.
            • 2001-2007 Head of the laboratory and professor in the same Department (Dermatology, Columbia University, New York
              Signal transduction pathways in normal skin and skin neoplastic/cornification disorders; skin regeneration; the role of environmental stress in skin pathology with major focus on environmentally-regulated dioxin receptor (AhR) and hypoxia-induced factor (HIF) pathways.
            • 2008-2012 Principal Investigator, Head of the laboratory, Scientific Lead in Skin Cancer Group, Division of Medical Sciences, University of Dundee, Dundee, UK.
              Role of environmental factors (hypoxia, UV light and AhR-activating xenobiotics) in control of HIF/AhR/ARNT machinery in the skin; interactions between AhR and HIF pathways and their role in skin aging, skin stem cell activity, regeneration and in pathogenesis of environmentally-modulated skin disorders (cancer, psoriasis, barrier function, desquamation, hair loss); interactions between AhR/HIF and retinoid-induced pathways.
            • 2013-current Head of the laboratory of Tissue engineering, Kurchatov complex of NBICS technologies, Kurchatov institute, Moscow, Russia
              Mechanisms of organogenesis and regeneration in mammals, tissue engineering.

            Research interests
            • Fundamental and applied aspects of epithelial biology
            • molecular mechanisms of epithelial cell response to micro- and macro-environmental factors
            • role of hypoxia pathway (HIF-responsive gene battery) in epithelial cell transformation and migration, stem cell homeostasis, and stromal angiogenesis
            • bioengineering of skin and respiratory epithelium
            • the role of environmental factors in skin and hair follicle regeneration, senescence and disease
            • novel therapeutic targets for pharmaceutical intervention in skin disorders, wound healing and aging.
            Berlin, Germany
            Victor Tarabykin
            MD, PhD
            Professor of Cellular Neurobiology
            Director Institute of Cell Biology and Neurobiology, Charité – Universitätsmedizin Berlin
            Leading Scientist and Director of Biomedical Cluster, Lobachevsky State University of Nizhny Novgorod
              Magdeburg, Germany
              Inna Lavrik
              Professor
              Head of Translational Inflammation Research, Medical Faculty, Otto von Guericke University, Magdeburg

              Head of laboratory of systems biology of cell death, Novosibirsk Institute of Cytology and Genetics
              Leading scientist, Faculty of Fundamental Medicine, Moscow State University

              The major scientific focus of Prof. Lavrik is on the molecular mechanisms governing the function of macromolecular complexes in death receptor networks, their posttranslational modifications and computational modeling of apoptosis pathways. She has made major contributions to the understanding of the molecular mechanisms of activation of the CD95 death-inducing signalng complex (DISC) as well as performed a number of pionerring studies in the field of systems biology of apoptosis.

              Professor Inna Lavrik has been working in the cell death research since 2000. She did postdoctoral research at the Division of Immunogenetics led by Prof. Peter H Krammer at DKFZ (German Cancer Research Center) in Heidelberg. She became a group leader at the same deparment in 2005. Since 2007 she has been running her group on Systems Biology studies of apoptosis at Bioquant/Heidelberg. She accomplished her habilitation in 2010 in Heidelberg. In 2012 she was appointed Professor at the Medical Faculty of the Otto von Guericke University of Magdeburg. Currently she is head of Translational Inflammation Research located at the Institute of Systems Biology at the Otto von Guericke University of Magdeburg.

              Professor Lavrik is a member of the editorial board of the Nature group Journal Cell Death and Discovery, Frontiers in Cell death and the Russian Journal of Genetics.

              Research interests
              • regulation of apoptotic and non-apoptotic signaling
              • cell death pathways in inflammation and cancer
              • regulation of cell death pathways at the single cell level
              • regulation of cell death pathways via posttranslational modifications
              • drug design targeting cell death pathways
              • computational modeling of cell death pathways.
                  St. Petersburg, Russia
                  Pavel Gershovich
                  BIOCAD Biotechnology company
                  Head of Cytology laboratory in the Department of advanced research projects

                  Head of Cytology laboratory in the Department of advanced research projects since 2016. Pavel has over 15 years experience in cell and molecular biology. At the moment, he is specialized in the nonclinical development of gene and cell-based therapies.

                  Research interests
                  • Gene therapy
                  • Cell based therapy
                  • Regenerative medicine
                  • In vivo and ex vivo gene delivery.
                      Conference Program
                      Wednesday, April 11
                      Thursday, April 12
                      Friday, April 13
                      11 April | Wednesday


                      REGISTRATION

                      12:00-15:00
                      OPENING SESSION
                      12 April | Thursday
                      BASIC PROBLEMS OF CELL RESEARCH
                      CELLULAR MODELS OF HUMAN DISEASES
                      BIO-RAD SPONSORED LUNCH
                      THE TASTES OF BIO-RAD CELL CULTURE SOLUTIONS
                      ORGANOIDS AND TISSUES ENGINEERING
                      17:20-18:20
                      Poster session
                      13 April | Friday
                      GENOME EDITING
                      BEST PRACTICE IN CELL THERAPY AND CELL PRODUCTS DEVELOPMENT
                      SARTORIUS SPONSORED LUNCH-SYMPOSIUM

                      ROUND TABLE
                      PERSPECTIVES AND CHALLENGES IN BIOMEDICAL CELL TECHNOLOGY DEVELOPMENT
                      Commitees
                      CHAIRS
                      Prof. Andrey Vasiliev — сhair
                      Ph.D., Sci.D., Corresponding member of the Russian Academy of Sciences, Director of Koltzov Institute of Developmental Biology RAS

                      Dr. Alexey Tomilin — сo-сhair
                      Ph.D., Sci.D., Corresponding member of the Russian Academy of Sciences, Head of Laboratory Molecular Biology of Stem Cells, Institute of Cytology RAS

                      Olga Seredkina — сo-сhair
                      General Manager, OPTEC Company
                      INTERNATIONAL ADVISORY BOARD
                      Prof. Nikolay Nikolsky
                      Sci.D., Academician of the Russian Academy of Sciences, Institute of Cytology RAS, St. Petersburg, Russia

                      Alexey Bersenev
                      Director, Advanced Cell Therapy Lab at Yale University Greater New York City Area

                      Prof. Dr. Hans Schöler
                      Max Planck Institute for Molecular Biomedicine, Münster
                      PROGRAM COMMITEE
                      Dr. Alexey Tomilin, Head of Program Committee
                      Ph.D., Sci.D., Corresponding member of the Russian Academy of Sciences, Head of Laboratory Molecular Biology of Stem Cells, Institute of Cytology RAS

                      Dr. Ekaterina Vorotelyak
                      Ph.D., Sci.D., Corresponding member of the Russian Academy of Sciences, Head of Laboratory of cell biology, Koltzov Institute of Developmental Biology RAS

                      Dr. Natalia Mikhailova
                      Ph.D., Sci.D., Head of Cell Technologies Center, Institute of Cytology RAS

                      Prof. Maria Alexandrova
                      PhD., Sci D., Head of the Group of Experimental Neurobiology, Koltzov Institute of Developmental Biology RAS

                      Tamara Malygina
                      Head of Cell Technologies SBU, OPTEC
                      Venue
                      CTERP Conference takes place in Novotel Moscow City. It's a part of The Moscow International Business Centre and located on the Presnenskaya embankment of the Moscow River, approximately 4 kilometers west of Red Square, and just east of the Third Ring Road.

                      Presnenskaya Naberezhnaya 2
                      MOSCOW - RUSSIAN FEDERATION
                      Delovoy Tsentr Station of Moscow Metro
                      GPS. N 55° 44' 53.05'' E 37° 32' 12.66''
                      Conference support
                      Grant number 18-04-20012
                      Provides targeted diversified support to leading groups of scientists for researches in all the principal directions of fundamental science
                      Organizators
                      Organizing committee
                      Ekaterina Kutuzova
                      Head of Marketing at OPTEC, Moscow, Russia

                      Marina Habarova
                      Academic Secretary at Koltzov Institute of Developmental Biology RAS, Moscow

                      Ekaterina Volina
                      Koltzov Institute of Developmental Biology RAS, Moscow

                      Mikhail Khotin
                      PhD, Research Fellow at Institute of Cytology RAS, St.Petersburg

                      Anna Koltsova
                      Institute of Cytology RAS, St.Petersburg

                      Anna Sypkova
                      Digital Marketing specialist at OPTEC, Moscow, Russia

                      cterp@optecgroup.com